KMID : 1202020090020020135
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Journal of Korean Thyroid Association 2009 Volume.2 No. 2 p.135 ~ p.138
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Postoperative Findings of the Thyroid Nodules without Definite Cytological Evidence of Malignancy, but Growing Rapidly during the Observation Period
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Kim Eui-Young
Kim Won-Gu Kim Tae-Yong Gong Gyung-Yup Ryu Jin-Sook Yoon Jong-Ho Hong Suck-Joon Kim Won-Bae Shong Young-Kee
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Abstract
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Background and Objectives : Fine needle aspiration (FNA) cytology is the best test to diagnose malignancy in thyroid nodules. However, cytologic interpretation of FNA specimens is difficult in case that follicular neoplasm is suggested. The aim of this study was to evaluate the rate of malignancy in thyroid nodules which were cytologically diagnosed as benign at the first FNA cytology but the size of nodules increased during the observation period.
Materials and Methods :Patients who underwent thyroid surgery in Asan Medical Center from 1996 to 2001 were enrolled. Patients who diagnosed as benign at the first FNA cytology and relatively rapid increase in the nodule size during the observation period were included in this retrospective study.
Results:Total 283 patients were included in this study. Their mean age was 42 years and mean tumor size was 4.89 cm (range 2.0¡12.0 cm). In pathologic results, 223 (80.9%) patients had benign thyroid nodules with 191 nodular hyperplasia, 37 follicular adenomas and 1 hashimoto¡¯s thyroiditis, respectively. Fifty four patients (19.1%) had malignancy with 35 follicular carcinomas, 17 papillary thyroid carcinomas and 2 poorly differentiated carcinomas, respectively.
Conclusion: Surgical treatment could be recommended for patients with significant increase in size of thyroid nodule, even though the results of their initial FNA were benign.
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KEYWORD
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Thyroid nodules, Fine needle aspiration, Thyroid neoplasm
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